History of the Syndrome

Before we extend our journey lets get to know first with the background of this syndrome. This disease was identified in 1955 by Dr. G.I.M Swyer of University College Hospital in London. In his research, he stated that Swyer syndrome is a genetic condition of an individual who born with chromosome XY which it is a male chromosome pattern with a female physical appearance and  it also known as XY gonadal dsygenesis. 

Essentially, the person has female external genitalia such as uterus and a Fallopian tube, but the gonads (ovaries or testes) are not operating the way it should.  Along the other tangent, it is a case of intersex condition which is there is a difference between the external genitals and the internal genitals which lead to the disorder sex development of an individual.

Most of experts addressed the disease with an older term as ‘Hermaphroditism’ which taken from the names of Greek gods Hermes and Aphrodite used to imply a person is both fully male and fully female. Research from U.S National Library of Medicine found the figure of people who suffers from this uncommon disease is around 1 in 30,000 people.  

Figure 2.0: Parent chromosome; 46 chromosomes: 23 pairs, one set from each parent

Figure 2.1: A person with 2 X chromosome (46,XX) is female and a person with an X and a Y (46,XY) is                                                                         a male